CD180 抗体
Quick Overview for CD180 抗体 (ABIN614758)
抗原
See all CD180 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects CD180.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure by SDS-PAGE
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免疫原
- Human tonsillar B cells
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亚型
- IgG1
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anti-CD180 Molecule (CD180) (AA 24-220) antibody
CD180 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) (Internal Region) antibodyCD180 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibody (APC)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 APC
anti-CD180 Molecule (CD180) antibody (PE)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 PE
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (N-Term) antibodyCD180 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (C-Term) antibodyCD180 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CD180 (CD180 Molecule (CD180))
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别名
- CD180 / RP105
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背景
- CD180, also known as RP105 (or Bgp95, LY64) is a type I membrane glycoprotein of Toll-like receptor (TLR) family. Its cytoplasmic tail is short and unlike the TLRs, it lacks the TIR domain. CD180 expression is dependent on the coexpression of its helper molecule, MD-1 , and mirrors that of TLR4 on antigen-presenting cells. CD180 regulates recognition of LPS and signaling in B cells, via interacting directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligands. Ligation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein
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基因ID
- 4064
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NCBI登录号
- NP_005573
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UniProt
- Q99467
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途径
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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